Python is a powerful weapon that can quickly melt enemies. It’s not the easiest weapon to get, so here’s everything you need to know to unlock the Python in The First Descendant.
How to unlock Python in The First Descendant
Python is an Ultimate submachine gun in The First Descendant, like Thunder Cage. To get the weapon, you must research it at Anais in Albion using the following materials: Python Polymer Syncytium Blueprint, Python Synthetic Fiber Blueprint, Python Nano Tube Blueprint, and Python Blueprint.
The first three materials have their own crafting recipes that include a bunch of resources and an item from the Amorphous Material. The research of every individual part takes two hours, and the weapon itself takes four hours. You also need 250,000 Gold for all of the research.
Here’s how to get every core item for Python in The First Descendant:
| Material | Source |
|---|---|
| Python Polymer Syncytium | Intercept Battle (Normal): Devourer (Amorphous Material Pattern: 029) Intercept Battle (Normal): Swamp Walker (Amorphous Material Pattern: 044) Abyssal Void Fusion Reactor void mission in the Grand Square in Kingston (Hard) Abyssal Void Fusion Reactor void mission in the Vermillion Waste in Agna Desert (Hard) |
| Python Synthetic Fiber | Intercept Battle (Normal): Grave Walker (Amorphous Material Pattern: 005) Intercept Battle (Normal): Stunning Beauty (Amorphous Material Pattern: 009) Intercept Battle (Hard): Swamp Walker (Amorphous Material Pattern: 096) Intercept Battle (Hard): Obstructer (Amorphous Material Pattern: 105) |
| Python Nano Tube | Intercept Battle (Normal): Pyromaniac (Amorphous Material Pattern: 039) Intercept Battle (Hard): Executioner (Amorphous Material Pattern: 059) Void Fusion Reactor void mission in the Repository in Sterile Land (Normal) Abyssal Void Fusion Reactor void mission in the Hatchery in White-night Gulch (Hard) |
| Python Blueprint | Intercept Battle (Normal): Dead Bride (Amorphous Material Pattern: 025) Abyssal Void Fusion Reactor void mission in the Ruins in Vespers (Hard) Abyssal Void Fusion Reactor void mission in the Defense Line in Fortress (Hard) Abyssal Void Fusion Reactor void mission in the Repository in Sterile Land (Hard) |
What does Python do in The First Descendant?
The Python submachine gun comes with a Unique Ability called Python Instinct. Hitting a weak point inflicts the Prey debuff on the target enemy that can stack for up to 20 stacks. For each stack of Prey, the target’s Toxin and Non-Attribute resistances are reduced.
This weapon is all about hitting weak points and buffing your Weak Point Damage, as it doesn’t have much Critical Hit Rate. You can use it on its own or pair it with the Descendant, like Freyna, to further improve your Toxic damage.
