Season Two of Diablo 4 is better than ever with the improved end-game bosses, which means there’s even more loot to grab. Depending on the endgame boss, you’ll get boss-specific items and different class-specific loot drops.
Here is the list of unique items that drop from these endgame bosses:
Echo of Varshan unique item loot drops
Echo of Varshan has a nice variety of uber unique item drops, but the ring Mother’s Embrace is a particularly nice grab thanks to its stat boosts.
| Class | Unique Item |
| All Classes | Frostburn Mother’s Embrace |
| Barbarian unique items | 100,000 Steps Fields of Crimson Gohr’s Devastating Grip Rings of Red Furor |
| Druid unique items | Greatstaff of the Crone Mad Wolf’s Flee Vasily’s Prayer Airidah’s Inexorable Will |
| Necromancer unique items | Bloodless Scream Deathless Visage Deathspeaker’s Pendant Ring of the Sacrilegious Soul |
| Sorcerer unique items | Esu’s Heirloom Raiment of the Infinite The Staff of Endless Rage Tal Rasha’s Iridescent Loop |
| Rogue unique items | Condemnation Eyes in the Dark Skyhunter Writing Band of Trickery |
Varshan isn’t too challenging to beat if you stay behind him and avoid his frontal attacks. It’s also a good idea to use poison-resistant elixirs to nullify the incoming poison damage.
Grigoire unique item loot drops
New to season 2, Grigoire doesn’t only drop unique weapons and armor. Defeating this monster could actually give you a unique armor for your mount called the Demonbinder.
| Class | Unique Item |
| All Classes | Penitent Greaves The Butcher’s Cleaver Demonbinder (Mount armor) |
| Barbarian unique items | Ancient’s Oath Battle Trance Rage of Harrogath Ramaladni’s Magnum Opus The Butcher’s Cleaver |
| Druid unique items | Hunter’s Zenith Insatiable Fury The Butcher’s Cleaver Waxing Gibbous |
| Necromancer unique items | Blood Artisan’s Cuirass Greaves of the Empty Tomb Howl from Below |
| Sorcerer unique items | Gloves of the Illuminator Iceheart Brais The Staff of Lam Esen |
| Rogue unique items | Grasp of Shadow Windforce Word of Hakan |
Although Grigoire’s lightning grid attack is tricky to avoid, it also presents a great opportunity to deal damage. If you can get close enough to him during this attack, Grigoire actually stands completely still. Again, it’s tricky to navigate that lightning grid, but, if you see him starting up the move, try to make your move.
Lord Zir unique item loot drops
Lord Zir has loads of unique armor and weapons, but there’s a unique cosmetic you can acquire as well. The Diadem of the Ancient Helm is only aesthetic, but perhaps it’ll be what completes your character’s look.
| Class | Unique Item |
| All Classes | Penitent Greaves Razorplate Temerity The Diadem of the Ancient Helm (cosmetic armor item) |
| Barbarian unique items | Gohr’s Devastating grips Overkill Rage of Harrogath Ramaladni’s Magnum Opus The Butcher’s Cleaver |
| Druid unique items | Fleshrender Mad Wolf’s Flee Vasily’s Prayer Greatstaff of the Crone The Butcher’s Cleaver |
| Necromancer unique items | Blood Artisan’s Cuirass Deathless Visage Greaves of the Empty Tomb Lidless Wall |
| Sorcerer unique items | Esadora’s Overflowing Cameo The Staff of Endless Rage Iceheart Brais Raiment of the Infinite |
| Rogue unique items | Asheara’s Khanjar Eyes in the Dark Grasp of Shadow Skyhunter |
Once you’ve summoned Lord Zir with Exquisite Blood, you’ll want to avoid his frontal attacks, kill his summoned vampires, and use an elixir of shadow resistance to help mitigate incoming shadow damage.
Beast in Ice unique item loot drops
If you’re hoping to jazz up the look of your mount, the Beast in Ice has the chance to drop the Skull Torch and Fell Steed mount trophies.
| Class | Unique Item |
| All Classes | Frostburn Fists of Fate Mother’s Embrace Tassets of the Dawning Sky Skull Torch (mount trophy) Fell Steed (mount trophy) |
| Barbarian unique items | 100,000 Steps Ancients’ Oath Battle Trance Fields of Crimson Hellhammer |
| Druid unique items | Hunter’s Zenith Insatiable Fury Storm’s Companion Waxing Gibbous |
| Necromancer unique items | Bloodless Scream Deathspeaker’s Pendant Howl from Below Ring of Mendeln |
| Sorcerer unique items | The Staff of Lam Esen Esu’s Heirloom Gloves of the Illuminator The Oculus |
| Rogue unique items | Condemnation Eaglehorn Word of Hakan Windforce |
Duriel unique item loot drops
In season 2, Duriel is the go-to uber boss for dropping unique items. In addition to the heaps of weapons and armor, you can also possibly acquire the Smoldering Brimstone Mount.
| Class | Unique Item |
| All Classes | Andariel’s Visage (Uber) Banished Lord’s Talisma Flickerstep Boots Godslayer Crown Harlequin Crest (Uber) Melted Heart of Selig (Uber) Ring of Starless Skies (Uber) Soulbrand Tibault’s Will X’Fal’s Corroded Signet Smoldering Brimstone (mount) |
| Barbarian unique items | Azurewrath Doombringer (Uber) The Grandfather (Uber) Tuskhelm of Joritz, the Mighty |
| Druid unique items | Ahavarion, Spear of Lycander (Uber) Dolmen Stone Tempest Roar |
| Necromancer unique items | Black River Blood Moon Breeches Doombringer The Grandfather (Uber) |
| Sorcerer unique items | Ahavarion, Spear of Lycander (Uber) Blue Rose Flamescar |
| Rogue unique items | Cowl of the Nameless Doombringer Scoundrel’s Leathers |
Duriel is the only endgame boss who can drop Uber unique items, so you should strive to defeat him as many times as possible in Season Two: Season of Blood.
Uber Lilith unique item loot drops
Even though Uber Lilith is the strongest boss in Diablo 4, she doesn’t drop too many exciting rewards, and if you’ve killed her once, you won’t get any additional loot. For the first Uber Lilith death, you will get the following:
- ‘Doom’ and ‘Lilith’s’ titles
- Reins of the Bloody Liquid Steed
- Random Legendary items
- Random Legendary x2
- Blood Liquid Mount
In addition to these drops, you will also get materials to summon the next endgame boss. So, if you’re the one to summon the boss, be sure to pick up those items, as you’re the only one who can get these summoning materials.
These are all the endgame boss unique items you can get as drops in Diablo 4’s second season, Season of Blood. Happy hunting!
